Bradley Cooper has split with on-again off-again girlfriend Zoe Saldana for the second time. After taking a break in March 2012, the two reconciled and broke up again just before the holidays. The two starred together in The Words. Saldana and her longtime love,Keith Britton, split in November 2011. Prior to his relationship with the Saldana, Cooper dated Renee Zellweger for two years and briefly datedJennifer Lopez and Olivia Wilde. He was also married to actress Jennifer Esposito for four months from 2006 to 2007.